Part I: Test Plan

General Anatomy

1.   Topographical Anatomy (8%)

• Planes of the body and anatomical terminology
• Head and neck
• Back and thorax
• Abdomen, pelvis and perineum
• Upper and lower limbs
• Integument (including histology)

2.   Osteology of the Appendicular Skeleton (15%)

• Upper limb and shoulder girdle
• Lower limb and pelvis
• Development
• Histology

3.   Arthrology and Syndesmology of the Appendicular Skeleton (15%)

• Classification of joints
• Articulations of the appendicular skeleton
• Biomechanics

4.   Myology of the Appendicular Skeleton (18%)

• Upper limb and shoulder (including innervation)
• Lower limb and pelvic girdle (including innervation)
• Development
• Structure and histology

5.   Cardiovascular and Lymphatic Systems (13%)

• Heart
• Arteries
• Veins
• Lymphatic vessels and lymphoid tissue (including spleen and thymus)
• Development
• Histology

6.   Digestive System (10%)

• Oral cavity and pharynx
• Digestive viscera
• Development
• Histology

7.   Respiratory System (8%)

• Nose and sinuses
• Larynx, trachea and bronchi
• Lungs, pleura and mediastinum
• Development
• Histology

8.   Urogenital System (8%)

• Urinary organs
• Male reproductive organs
• Female reproductive organs
• Development
• Histology

9.   Endocrine System (5%)

• Endocrine glands and tissues
• Development
• Histology

Spinal Anatomy

1.   Osteology of the Axial Skeleton (19%)

• Skull
• Vertebral column
• Ribs and sternum
• Development

2.   Myology of the Axial Skeleton (15%)

• Face and head
• Back and neck
• Thorax and abdomen
• Pelvis and perineum
• Development

3.   Arthrology and Syndesmology of the Axial Skeleton (13%)

• Classification of joints
• Articulations of the axial skeleton
• Biomechanics

4.   Anatomy of the Central Nervous System and Related Structures (23%)

• Cerebrum
• Brainstem and cerebellum
• Spinal cord and meninges
• Vascular supply and relationships
• Ventricles and cerebrospinal fluid
• Development
• Histology

5.   Anatomy of the Peripheral and Autonomic Nervous Systems (21%)

• Spinal nerves and plexuses
• Cranial nerves
• Visceral innervation
• Cutaneous innervation
• Development
• Histology

6.   Organs of Special Senses (9%)

• Vision
• Audition and equilibrium
• Olfaction
• Gustation
• Development
• Histology

Physiology

1.   Neurophysiology (22%)

• Membrane potentials, action potentials, and synaptic transmission
• Motor function
• Sensory function
• Autonomic function
• Higher cortical function
• Special senses

2.   Muscle Physiology (15%)

• Cardiac muscle
• Skeletal muscle
• Smooth muscle

3.   Cardiovascular Physiology (15%)

• Cardiac pump
• Electrophysiology of the heart
• Hemodynamics
• Regulation of circulation
• Circulation in organs
• Lymphatics
• Hematology and immunity

4.   Respiratory Physiology (9%)

• Mechanics of breathing
• Ventilation, lung volumes and capacities
• Regulation of respiration
• O₂ and CO₂ transport
• Gas exchange

5.   Body Fluids and Renal Physiology (10%)

• Regulation of body fluids/ micturition
• Glomerular filtration
• Tubular exchange
• Acid-base balance

6.   Gastrointestinal Physiology (9%)

• Ingestion/motility
• Digestion/secretion
• Absorption
• Regulation of GI function

7.   Reproductive Physiology (5%)

8.   Endocrine Physiology (9%)

• Secretion of hormones
• Action of hormones
• Regulation

9.   Exercise and Sports Physiology (6%)

Chemistry

1.   Carbohydrates (18%)

• Metabolism
  • Catabolic pathways
  • Anabolic pathways
• Chemistry
  • Structure
  • Properties
  • Function
• Nutritional concepts
  • Food sources
  • Digestion

2.   Lipids (18%)

• Metabolism
  • Catabolic pathways
  • Anabolic pathways
• Chemistry
  • Structure
  • Properties
  • Function
  • Transport
• Nutritional Concepts
  • Food sources
  • Digestion

3.   Proteins, Amino Acids and Peptides (17%)

• Amino acid metabolism
  • Catabolic pathways
  • Anabolic pathways
• Chemistry
  • Structure
  • Properties
  • Function
• Nutritional concepts
  • Food sources
  • Digestion

4.   Enzymes (7%)

• Classification and function
• Kinetics and regulation

5.   Hormones (6%)

• Metabolic effects of specific hormones
  • Carbohydrate metabolism
  • Lipid metabolism
  • Protein metabolism
• General properties
  • Chemistry
  • Mechanism of action

6.   Nucleotides and Nucleic Acids (10%)

• Metabolism of purines and pyrimidines
• Chemistry
  • Structure
  • Properties
  • Function
• DNA, RNA and protein synthesis

7.   Vitamins and Minerals (14%)

• Chemistry
  • Structure
  • Properties
  • Function
  • Coenzyme precursors
• Nutritional concepts
  • Food sources
  • Absorption
  • Storage

8.   Biochemical Energetics (10%)

• Basic concepts
  • High-energy phosphate compounds
  • Oxidation-reduction reactions
• Krebs cycle
• Oxidative phosphorylation and electron transport system

Pathology

1.   Fundamentals of Pathology (21%)

• Disease at the cellular level
• Inflammation and repair
• Neoplasia
• Hemodynamic disorders

2.   Genetic and Congenital Disorders (4%)

• Chromosomal disorders
• Inborn errors of metabolism
• Congenital disorders

3.   Disorders of the Immune System (7%)

• Hypersensitivity reactions
• Autoimmune diseases
• Immunologic deficiencies

4.   Environmental and Nutritional Diseases (5%)

5.   Disorders of the Musculoskeletal System (18%)

• Bone
• Joint
• Muscle

6.   Disorders of the Nervous System (11%)

• Central nervous system
• Peripheral nervous system

7.   Diseases of the Organ Systems (34%)

• Cardiovascular
• Gastrointestinal
• Respiratory
• Genitourinary
• Endocrine
• Blood and lymphatics

Microbiology

1.   Immunology (23%)

• Cells of the immune system
• Antigens, antibodies and complement
• Hypersensitivities and immunopathologies
• Immunization/vaccination
• Assessment of immune responses/serology

2.   Bacteria (20%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

3.   Viruses and Prions (15%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

4.   Fungi (10%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

5.   Parasites (10%)

• Structure and biochemical characteristics
• Resistance, genetics, antigenicity, and pathogenicity
• Communicable and infectious diseases
• Reservoirs of infection and modes of transmission

6.   Epidemiology and Disease Control (22%)

• Health agencies and reporting/monitoring
• Prevention, identification and control methods for communicable diseases
• Population health assessments
• Emerging diseases